Article
Patient with high-risk GIST not associated with c-KIT mutations: same benefit from adjuvant therapy?
Anti-cancer drugs - 1 Jun 2012
Izquierdo Maria Eugenia Ortega, Bonastre Maria Teresa Taberner
Abstract excerpt
A patient was diagnosed with neurofibromatosis type 1 (NF1) and gastrointestinal stromal tumour (GIST). This is not simply a coincidence; numerous molecular and genetic studies have established a close relationship between the two disorders, suggesting that GIST should be included in the clinical spectrum of NF1. In NF1 presenting GIST, the tumour usually develops in the small intestine. We present a 51-year-old...
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