Article
Evaluation of ES-derived neural progenitors as a potential source for cell replacement therapy in the gut.
BMC gastroenterology - 26 Jun 2012
Sasselli Valentina, Micci Maria-Adelaide, Kahrig Kristen M, Pasricha Pankaj Jay
Abstract excerpt
BACKGROUND: Stem cell-based therapy has recently been explored for the treatment of disorders of the enteric nervous system (ENS). Pluripotent embryonic stem (ES) cells represent an attractive cell source; however, little or no information is currently available on how ES cells will respond to the gut environment. In this study, we investigated the ability of ES cells to respond to environmental cues derived from...
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