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Article

Investigating the role of pain-modulating pathway genes in musculoskeletal pain.

European journal of pain (London, England) - 1 Jan 2013

Holliday K L, McBeth J, Macfarlane G, Huhtaniemi I T, Bartfai G, Casanueva F F, Forti G, Kula K, Punab M, Vanderschueren D, Wu F C, Thomson W

Abstract excerpt

AIMS: The aim of this study was to determine if genetic variation in the pain-modulating gene DREAM and its pathway genes influence susceptibility to reporting musculoskeletal pain in the population. METHODS: Pairwise tag single nucleotide polymorphisms (SNPs) in DREAM, PDYN and OPRK1 were genotyped in a UK population-based discovery cohort in whom pain was assessed using blank body manikins at three time points....

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Source

Identifiers

PMID: 22730276
DOI: 10.1002/j.1532-2149.2012.00163.x

Genes

OPRK1
PDYN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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