Article
Does familial clustering of risk factors for long-term diabetic complications leave any place for genes that act independently?
Journal of cardiovascular translational research - 1 Aug 2012
Paterson Andrew D, Bull Shelley B
Abstract excerpt
Long-term complications of type 1 diabetes, including nephropathy and retinopathy, share diabetes duration and hyperglycemia as major risk factors. Cross-sectional studies of sibpairs, both with type 1 diabetes, have shown familial clustering of specific complications, leading to the hypothesis that there are genetic contributors. However, because of the cross-sectional design of these studies, they were not able...
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