Article
An initiation codon mutation as a cause of a beta-thalassemia.
Hemoglobin - 1 Jan 1990
Jankovic L, Efremov G D, Josifovska O, Juricic D, Stoming T A, Kutlar A, Huisman T H
Abstract excerpt
During the course of a screening program for beta-thalassemia mutations among beta-thalassemia heterozygotes in Yugoslavia we observed a mutation (ATG----ACG) in the initiation codon of the beta-globin gene which has not been described before. The abnormality was initially detected through mappin...
Topics
- Adult
- Base Sequence
- Codon
- Female
- Heterozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Peptide Chain Initiation, Translational
- Polymorphism, Genetic
- Thalassemia