Article
Detection of rare and possibly carcinogenic human papillomavirus genotypes as single infections in invasive cervical cancer.
The Journal of pathology - 1 Dec 2012
Geraets Daan, Alemany Laia, Guimera Nuria, de Sanjose Silvia, de Koning Maurits, Molijn Anco, Jenkins David, Bosch Xavier, Quint Wim
Abstract excerpt
The contribution of carcinogenic human papillomavirus (HPV) types to the burden of cervical cancer has been well established. However, the role and contribution of phylogenetically related HPV genotypes and rare variants remains uncertain. In a recent global study of 8977 HPV-positive invasive cervical carcinomas (ICCs), the genotype remained unidentified in 3.7% by the HPV SPF10 PCR-DEIA-LiPA25 (version 1)...
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