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Article

A multicentre study of acute kidney injury in severe sepsis and septic shock: association with inflammatory phenotype and HLA genotype.

PloS one - 1 Jan 2012

Payen Didier, Lukaszewicz Anne-Claire, Legrand Matthieu, Gayat Etienne, Faivre Valérie, Megarbane Bruno, Azoulay Elie, Fieux Fabienne, Charron Dominique, Loiseau Pascale, Busson Marc

Abstract excerpt

BACKGROUND: To investigate the association between severity of acute kidney injury (AKI) and outcome, systemic inflammatory phenotype and HLA genotype in severe sepsis. METHODOLOGY/PRINCIPAL FINDINGS: Prospective multicenter observational study done in 4 intensive care units in two university hospitals. Severe sepsis and septic shock patients with at least 2 organ failures based on the SOFA score were classified:...

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Identifiers

PMID: 22701553
DOI: 10.1371/journal.pone.0035838
PMCID: PMC3368929

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MIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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