Article
Very low levels of HDL cholesterol and atherosclerosis, a variable relationship--a review of LCAT deficiency.
Vascular health and risk management - 1 Jan 2012
Savel Julia, Lafitte Marianne, Pucheu Yann, Pradeau Vincent, Tabarin Antoine, Couffinhal Thierry
Abstract excerpt
A number of epidemiological and clinical studies have demonstrated that plasma high-density lipoprotein (HDL) level is a strong inverse predictor of cardiovascular events. HDL is believed to retard the formation of atherosclerotic lesions by removing excess cholesterol from cells and preventing endothelial dysfunction. Lecithin cholesterol acyltransferase (LCAT) plays a central role in the formation and...
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