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Article

Maternal high-fat diet programs Wnt genes through histone modification in the liver of neonatal rats

13 Jun 2012

Abstract excerpt

Maternal high-fat (HF) diets during gestation and lactation have been shown to contribute to metabolic disorders in offspring. Molecular and epigenetic mechanisms underlying this connection may be essential for the prevention and treatment of the fetal origins of metabolic diseases. The current study examined the impact of maternal HF diets on Wnt signaling and histone modification in offspring. Time-pregnant...

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PMID: 22696509
DOI: 10.1530/jme-12-0046

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