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Article

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring

1 Jan 2009

Abstract excerpt

BACKGROUND: miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during pregnancy and lactation alters expression of key miRNAs in the offspring. RESULTS: We studied the effects of maternal HF diet on the adult offspring by feeding mice with...

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Birth, Development, and Health
Fatty Acid Research and Health
MicroRNA in disease regulation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19835573
DOI: 10.1186/1471-2164-10-478

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