Article
Hepatitis C virus genotype 4 responds better to pegylated interferon with ribavirin than genotype 1 in HIV-infected patients.
AIDS (London, England) - 24 Aug 2012
Mira José A, Rivero Antonio, de Los Santos-Gil Ignacio, López-Cortés Luis F, Girón-González José A, Márquez Manuel, Merino Dolores, del Mar Viloria María, Téllez Francisco, Ríos-Villegas María J, Omar Mohamed, Rivero-Juárez Antonio, Macías Juan, Pineda Juan A
Abstract excerpt
We assess the efficacy of pegylated interferon (peg-IFN) with ribavirin (RBV) and the predictors of sustained virological response (SVR) among HIV/hepatitis C virus genotype 4 (HCV-4)-coinfected patients. Thirty-nine (31.5%) of 124 individuals with HCV-4 achieved SVR compared with 103 (22.7%) of 453 individuals with HCV genotype 1 (P=0.046). Only interleukin-28B (IL28B) genotype CC was independently associated...
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