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Article

Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs.

Bioinformatics (Oxford, England) - 15 Jun 2012

Lee Seunghak, Xing Eric P

Abstract excerpt

MOTIVATION: As many complex disease and expression phenotypes are the outcome of intricate perturbation of molecular networks underlying gene regulation resulted from interdependent genome variations, association mapping of causal QTLs or expression quantitative trait loci must consider both additive and epistatic effects of multiple candidate genotypes. This problem poses a significant challenge to contemporary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22689753
DOI: 10.1093/bioinformatics/bts227
PMCID: PMC3371859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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