Article
[Analysis of the complete hepatitis B virus genomes in a patient for repeated seroconversion to anti-HBe antibody due to co-infection with two virus clones].
Rinsho byori. The Japanese journal of clinical pathology - 1 Apr 2012
Yukimasa Nobuyasu, Uzawa Ryuichi, Fukuchi Kunihiko
Abstract excerpt
We report a case of repeated seroconversion to anti-HBe antibody in a patient with chronic hepatitis B. We amplified and cloned sections of the hepatitis B virus (HBV) genes by polymerase chain reaction (PCR), and sequenced the PCR products. The results were analyzed by connecting all of the sequences to generate complete genomes. As a result, we confirmed the coexistence of two different HBV clones, both of...
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