Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The interplay of variants near LEKR and CCNL1 and social stress in relation to birth size.

PloS one - 1 Jan 2012

Ali Khan Anokhi, Rodriguez Alina, Sebert Sylvain, Kaakinen Marika, Cauchi Stéphane, Froguel Philippe, Hartikainen Anna-Liisa, Pouta Anneli, Järvelin Marjo-Riitta

Abstract excerpt

BACKGROUND: We previously identified via a genome wide association study variants near LEKR and CCNL1 and in the ADCY5 genes lead to lower birthweight. Here, we study the impact of these variants and social stress during pregnancy, defined as social adversity and neighborhood disparity, on infant birth size. We aimed to determine whether the addition of genetic variance magnified the observed associations....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth Weight
Share to Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Finland

Share to Maternal Age

Share to Regression Analysis

Share to Social Class

Share to Socioeconomic Factors

Share to Stress, Psychological

Source

Open in PubMed Open full text

Identifiers

PMID: 22685556
DOI: 10.1371/journal.pone.0038216
PMCID: PMC3369922

Genes

CCNL1
ADCY5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The interplay of variants near LEKR and CCNL1 and social stress in relation to birth size.PMID 22685556Read ↗

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.Semantic proximity Read ↗

Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters.Semantic proximity Read ↗

Stress and glucocorticoid treatment during pregnancy, early growth and metabolic outcomes in childhoodSemantic proximity Read ↗

An interaction between NDE1 and high birth weight increases schizophrenia susceptibility.Semantic proximity Read ↗

Absence of birth-weight lowering effect of ADCY5 and near CCNL, but association of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians.Semantic proximity Read ↗

Genetic origins of low birth weight.Semantic proximity Read ↗

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.Semantic proximity Read ↗

Invited commentary: two studies of genetic control of birth weight where large data sets were available.Semantic proximity Read ↗

Maternal physical, socioeconomic, and demographic characteristics and childbirth complications in rural lowland Nepal: Applying an evolutionary framework to understand the role of phenotypic plasticitySemantic proximity Read ↗

Trajectories in county-level Low Birthweight Rates and Associated Contextual Factors in the United States, 2016-2021Semantic proximity Read ↗

The association of maternal psychosocial stress with newborn telomere lengthSemantic proximity Read ↗

Interaction between birthweight and polymorphism in the calcium-sensing receptor gene in determination of adult bone mass: the Hertfordshire cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.