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Article

Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2013

Wu Yanrui, Yang Hongju, Yang Benguan, Yang Ke, Xiao Chunjie

Abstract excerpt

INTRODUCTION: The prolylcarboxypeptidase (PRCP) gene encodes a membrane protein that acts on angiotensin II (Ang II) and kallikrein to release vasoactive peptides. The chymase (CMA1) gene is important for Ang II generation. Therefore, the two genes might be involved in the pathogenesis of essential hypertension (EH). MATERIALS AND METHODS: Eleven tag single nucleotide polymorphisms (SNPs) in the PRCP gene and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22679278
DOI: 10.1177/1470320312448949

Genes

PRCP
CMA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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