Article
Motor restlessness, sleep disturbances, thermal sensory alterations and elevated serum iron levels in Btbd9 mutant mice.
Human molecular genetics - 15 Sept 2012
DeAndrade Mark P, Johnson Russell L, Unger Erica L, Zhang Li, van Groen Thomas, Gamble Karen L, Li Yuqing
Abstract excerpt
Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a sensory-motor neurological disorder with a circadian component. RLS is characterized by uncomfortable sensations in the extremities, generally at night or during sleep, which often leads to an uncontrollable urge to move them for relief. Recently, genomic studies identified single-nucleotide polymorphisms in BTBD9, along with three other...
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