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Article

Retrocochlear function of the peripheral deafness gene Cacna1d.

Human molecular genetics - 1 Sept 2012

Satheesh Somisetty V, Kunert Katrin, Rüttiger Lukas, Zuccotti Annalisa, Schönig Kai, Friauf Eckhard, Knipper Marlies, Bartsch Dusan, Nothwang Hans Gerd

Abstract excerpt

Hearing impairment represents the most common sensory deficit in humans. Genetic mutations contribute significantly to this disorder. Mostly, only malfunction of the ear is considered. Here, we assessed the role of the peripheral deafness gene Cacna1d, encoding the L-type channel Ca(v)1.3, in downstream processing of acoustic information. To this end, we generated a mouse conditional Cacna1d-eGFP(flex) allele....

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PMID: 22678062
DOI: 10.1093/hmg/dds217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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