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Article

SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion.

Diabetologia - 1 Sept 2012

Sansbury F H, Flanagan S E, Houghton J A L, Shuixian Shen F L, Al-Senani A M S, Habeb A M, Abdullah M, Kariminejad A, Ellard S, Hattersley A T

Abstract excerpt

AIMS: The gene SLC2A2 encodes GLUT2, which is found predominantly in pancreas, liver, kidney and intestine. In mice, GLUT2 is the major glucose transporter into pancreatic beta cells, and biallelic Slc2a2 inactivation causes lethal neonatal diabetes. The role of GLUT2 in human beta cells is contr...

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Identifiers

PMID: 22660720
DOI: 10.1007/s00125-012-2595-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22660720-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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