Article
Paradox of schizophrenia genetics: is a paradigm shift occurring?
Behavioral and brain functions : BBF - 31 May 2012
Doi Nagafumi, Hoshi Yoko, Itokawa Masanari, Yoshikawa Takeo, Ichikawa Tomoe, Arai Makoto, Usui Chie, Tachikawa Hirokazu
Abstract excerpt
BACKGROUND: Genetic research of schizophrenia (SCZ) based on the nuclear genome model (NGM) has been one of the most active areas in psychiatry for the past two decades. Although this effort is ongoing, the current situation of the molecular genetics of SCZ seems disappointing or rather perplexing. Furthermore, a prominent discrepancy between persistence of the disease at a relatively high prevalence and a low...
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