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Article

Is promiscuity associated with enhanced selection on MHC-DQα in mice (genus Peromyscus)?

PloS one - 1 Jan 2012

MacManes Matthew D, Lacey Eileen A

Abstract excerpt

Reproductive behavior may play an important role in shaping selection on Major Histocompatibility Complex (MHC) genes. For example, the number of sexual partners that an individual has may affect exposure to sexually transmitted pathogens, with more partners leading to greater exposure and, hence, potentially greater selection for variation at MHC loci. To explore this hypothesis, we examined the strength of...

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PMID: 22649541
DOI: 10.1371/journal.pone.0037562
PMCID: PMC3359288

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