Article
Inherited and acquired risk factors for venous thromboembolism.
Seminars in respiratory and critical care medicine - 1 Apr 2012
Baglin Trevor
Abstract excerpt
Venous thrombosis, or venous thromboembolism, comprises deep vein thrombosis with or without symptomatic pulmonary embolus. The development of symptomatic venous thrombosis is highly dependent on gene-environment interaction. In most instances this interaction results in hypercoagulability (the intermediate phenotype) sufficient to result in intraluminal clot formation (the disease phenotype). The genetic...
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