Article
HLA-DRβ1*04 typing by simple in-house PCR-SSP technique for rheumatoid arthritis patients.
Rheumatology international - 1 Apr 2013
Parasannanavar Devaraj Jatteppa, Yeola Avani, Pradhan Vandana, Rajyadhaksha Anjali, Ghosh Kanjaksha
Abstract excerpt
A strong association between rheumatoid arthritis (RA) and human leukocyte antigen (HLA) has been observed in many different populations and that accounts for approximately one-third of the genetic component of RA susceptibility. The greatest effect comes from DRβ1 gene where the strongest association has been found with DRβ1*04 (DR4) allele. As serology has some disadvantages over polymerase chain reaction...
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