Article
Tracing hepatitis B virus to the 16th century in a Korean mummy.
Hepatology (Baltimore, Md.) - 1 Nov 2012
Kahila Bar-Gal Gila, Kim Myeung Ju, Klein Athalia, Shin Dong Hoon, Oh Chang Seok, Kim Jong Wan, Kim Tae-Hyun, Kim Seok Bae, Grant Paul R, Pappo Orit, Spigelman Mark, Shouval Daniel
Abstract excerpt
UNLABELLED: A rare find of a mummified child from the 16th century AD, in Korea, with relatively preserved organs, enabled a search for ancient hepatitis B virus (aHBV) DNA sequences from laparoscopic-derived liver biopsies. Analysis of the complete aHBV genome (3,215 base pairs) revealed a unique HBV genotype C2 (HBV/C2) sequence commonly spread in Southeast Asia, which probably represents an HBV that infected...
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