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Neolithic and medieval virus genomes reveal complex evolution of hepatitis B

10 May 2018

Abstract excerpt

The hepatitis B virus (HBV) is one of the most widespread human pathogens known today, yet its origin and evolutionary history are still unclear and controversial. Here, we report the analysis of three ancient HBV genomes recovered from human skeletons found at three different archaeological sites in Germany. We reconstructed two Neolithic and one medieval HBV genome by de novo assembly from shotgun DNA...

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Share to Bacteriophages and microbial interactions
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PMID: 29745896
DOI: 10.7554/elife.36666

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