Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms of HO-1 and COX-1 are associated with aspirin resistance defined by light transmittance aggregation in Chinese Han patients.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Sept 2013

Li Xiao-li, Cao Jian, Fan Li, Wang Qiang, Ye Ling, Cui Chun-Ping, Wang Ya-Zhen, Liu Lin, Li Bin, Wu Ruo-Jun, Zhou Feng-chun, Zhang Jun-hong

Abstract excerpt

BACKGROUND: Cyclooxygenase 1 (COX-1), COX-2, and HO-1 are involved in the process of aspirin's effect. The genetic susceptibility of these enzymes to aspirin resistance (AR) is unclear. METHODS: A total of 431 patients took aspirin. Using arachidonic acid-induced light transmittance aggregation combined with adenosine diphosphate-induced light transmittance aggregation, 36 participants served for AR, 164...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclooxygenase 1

Share to Cyclooxygenase Inhibitors

Share to Heme Oxygenase-1

Share to Platelet Aggregation

Share to Platelet Aggregation Inhibitors

Share to Scattering, Radiation

Source

Identifiers

PMID: 22609818
DOI: 10.1177/1076029612444002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of HO-1 and COX-1 are associated with aspirin resistance defined by light transmittance aggregation in Chinese Han patients.PMID 22609818Read ↗

Aspirin resistance: clinical significance and genetic polymorphism.Semantic proximity Read ↗

Frequency, risk factors, prognosis, and genetic polymorphism of the cyclooxygenase-1 gene for aspirin resistance in elderly Chinese patients with cardiovascular disease.Semantic proximity Read ↗

[Correlation analysis of aspirin resistance and cycloxygenase-1 haplotype in old Chinese patients with cardio-cerebrovascular diseases].Semantic proximity Read ↗

Interaction between COX-1 and COX-2 Variants Associated with Aspirin Resistance in Chinese Stroke Patients.Semantic proximity Read ↗

Genetic Association Study and Machine Learning to Investigate Differences in Platelet Reactivity in Patients with Acute Ischemic Stroke Treated with AspirinSemantic proximity Read ↗

A brief review on the mechanisms of aspirin resistance.Semantic proximity Read ↗

The emergent phenomenon of aspirin resistance: insights from genetic association studies.Semantic proximity Read ↗

Aspirin Resistance and Genetic PolymorphismsSemantic proximity Read ↗

The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysis.Semantic proximity Read ↗

Key Mutant Genes and Biological Pathways Involved in Aspirin Resistance in the Residents of the Chinese Plateau Area.Semantic proximity Read ↗

Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism.Semantic proximity Read ↗

Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.