Reciprocal induction of human dermal microvascular endothelial cells and human mesenchymal stem cells: time‐dependent profile in a co‐culture system

Abstract excerpt

OBJECTIVES: Angiogenesis is closely associated with osteogenesis where reciprocal interactions between endothelial and osteoblast cells play an important role in bone regeneration. For these reasons, the aim of this work was to develop a co-culture system to study in detail any time-dependent interactions between human mesenchymal stem cells (HMSC) and human dermal microvascular endothelial cells (HDMEC),...