Article
Direct cell-cell contact between mesenchymal stem cells and endothelial progenitor cells induces a pericyte-like phenotype in vitro.
BioMed research international - 1 Jan 2014
Loibl Markus, Binder Andreas, Herrmann Marietta, Duttenhoefer Fabian, Richards R Geoff, Nerlich Michael, Alini Mauro, Verrier Sophie
Abstract excerpt
Tissue engineering techniques for the regeneration of large bone defects require sufficient vascularisation of the applied constructs to ensure a sufficient supply of oxygen and nutrients. In our previous work, prevascularised 3D scaffolds have been successfully established by coculture of bone marrow derived stem cells (MSCs) and endothelial progenitor cells (EPCs). We identified stabilising pericytes (PCs) as...
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