Article
FcγRIIB-nt645+25A/G gene polymorphism and periodontitis in Japanese women with preeclampsia.
International journal of immunogenetics - 1 Dec 2012
Wang Y, Sugita N, Kikuchi A, Iwanaga R, Hirano E, Shimada Y, Sasahara J, Tanaka K, Yoshie H
Abstract excerpt
FcγRIIB contains a unique immunoreceptor tyrosine-based inhibition motif (ITIM) and functions as a negative feedback regulator of leucocyte activation and antibody production. We have previously reported FcγRIIB-nt645+25A/G gene polymorphism to be associated with prevalence and severity of periodontitis, FcγRIIB expression level on peripheral B lymphocytes and the serum IgG level against periodontopathic...
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