Article
Lower antibody response to Porphyromonas gingivalis associated with immunoglobulin G Fcgamma receptor IIB polymorphism.
Journal of periodontal research - 1 Dec 2008
Honma Y, Sugita N, Kobayashi T, Abiko Y, Yoshie H
Abstract excerpt
BACKGROUND AND OBJECTIVE: Human FcgammaRIIB is one of the receptors for immunoglobulin G (IgG) and suppresses the activation of B lymphocytes through cross-linking with the B cell receptor via immune complexes. This function of FcgammaRIIB is essential for the negative regulation of antibody prod...
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