Article
Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project.
Clinical pharmacology and therapeutics - 1 Jul 2012
Pulley J M, Denny J C, Peterson J F, Bernard G R, Vnencak-Jones C L, Ramirez A H, Delaney J T, Bowton E, Brothers K, Johnson K, Crawford D C, Schildcrout J, Masys D R, Dilks H H, Wilke R A, Clayton E W, Shultz E, Laposata M, McPherson J, Jirjis J N, Roden D M
Abstract excerpt
The promise of "personalized medicine" guided by an understanding of each individual's genome has been fostered by increasingly powerful and economical methods to acquire clinically relevant information. We describe the operational implementation of prospective genotyping linked to an advanced clinical decision-support system to guide individualized health care in a large academic health center. This approach to...
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