Article
Implementation of clopidogrel pharmacogenetic clinical decision support for a preemptive return of results program.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists - 11 Jun 2024
Aquilante Christina L, Trinkley Katy E, Lee Yee Ming, Crooks Kristy R, Hearst Emily C, Heckman Simeon M, Hess Kaitlyn W, Kudron Elizabeth L, Martin James L, Swartz Carolyn T, Kao David P
Abstract excerpt
PURPOSE: To describe our experiences implementing and iterating CYP2C19 genotype-guided clopidogrel pharmacogenetic clinical decision support (CDS) tools over time in the setting of a large health system-wide, preemptive pharmacogenomics program. SUMMARY: Clopidogrel-treated patients who are genetically predicted cytochrome P450 isozyme 2C19 (CYP2C19) intermediate or poor metabolizers have an increased risk of...
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