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Slow freezing and vitrification differentially modify the gene expression profile of human metaphase II oocytes

15 May 2012

Abstract excerpt

BACKGROUND: Cryopreservation is now considered as an efficient way to store human oocytes to preserve fertility. However, little is known about the effects of this technology on oocyte gene expression. The aim of this study was to examine the effect of the two cryopreservation procedures, slow freezing and vitrification, on the gene expression profile of human metaphase II (MII) oocytes. METHODS: Unfertilized MII...

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PMID: 22587994
DOI: 10.1093/humrep/des153

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