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Cryopreservation of Gametes and Embryos and Their Molecular Changes

8 Oct 2021

Abstract excerpt

The process of freezing cells or tissues and depositing them in liquid nitrogen at -196 °C is called cryopreservation. Sub-zero temperature is not a physiological condition for cells and water ice crystals represent the main problem since they induce cell death, principally in large cells like oocytes, which have a meiotic spindle that degenerates during this process. Significantly, cryopreservation represents an...

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PMID: 34639209
DOI: 10.3390/ijms221910864

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