Article
Confirmation of lymphomatous pulmonary involvement by immunophenotypic and gene rearrangement analysis of bronchoalveolar lavage fluid.
Mayo Clinic proceedings - 1 May 1990
Pisani R J, Witzig T E, Li C Y, Morris M A, Thibodeau S N
Abstract excerpt
Pathologic diagnosis of pulmonary involvement with lymphoma has traditionally necessitated open-lung biopsy in most cases. Specimens large enough to allow recognition of characteristic cytologic and architectural changes are usually not obtained bronchoscopically. Even when adequate biopsy specim...
Topics
- B-Lymphocytes
- Blotting, Southern
- Bronchoalveolar Lavage Fluid
- DNA Probes
- DNA, Neoplasm
- Gene Rearrangement, B-Lymphocyte, Light Chain
- Humans
- Immunohistochemistry
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Male
- Middle Aged
- Phenotype