Article
UGT1A1, SLCO1B1, and SLCO1B3 polymorphisms vs. neonatal hyperbilirubinemia: is there an association?
Pediatric research - 1 Aug 2012
Alencastro de Azevedo Laura, Reverbel da Silveira Themis, Carvalho Clarissa Gutierrez, Martins de Castro Simone, Giugliani Roberto, Matte Ursula
Abstract excerpt
BACKGROUND: Jaundice is a physiological phenomenon; however, severe hyperbilirubinemia occurs in only 5 to 6% of the healthy newborn population. It has been suggested that genetic variation could enhance the risk of hyperbilirubinemia when coexpressed with other icterogenic conditions. METHODS: The study included newborns with a gestational age of greater than 35 wk and weights greater than 2,000 g with...
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