Article
Reversing the resistance phenotype of the Biomphalaria glabrata snail host Schistosoma mansoni infection by temperature modulation.
PLoS pathogens - 1 Jan 2012
Ittiprasert Wannaporn, Knight Matty
Abstract excerpt
Biomphalaria glabrata snails that display either resistant or susceptible phenotypes to the parasitic trematode, Schistosoma mansoni provide an invaluable resource towards elucidating the molecular basis of the snail-host/schistosome relationship. Previously, we showed that induction of stress genes either after heat-shock or parasite infection was a major feature distinguishing juvenile susceptible snails from...
Topics
- Animals
- Biomphalaria
- Cercaria
- Disease Susceptibility
- Female
- HSP70 Heat-Shock Proteins
- Heating
- Host-Parasite Interactions
- Immunity, Innate
- Mice
- Phenotype
- Schistosoma mansoni
- Transcriptional Activation
