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Article

Charcot-Marie-Tooth disease: emerging mechanisms and therapies.

The international journal of biochemistry & cell biology - 1 Aug 2012

d'Ydewalle Constantin, Benoy Veronick, Van Den Bosch Ludo

Abstract excerpt

Charcot-Marie-Tooth disease is the most common inherited disorder of the peripheral nervous system. The disease is characterized by a progressive muscle weakness and atrophy, sensory loss, foot (and hand) deformities and steppage gait. While many of the genes associated with axonal CMT have been identified, to date it is unknown which mechanism(s) causes the disease. However, genetic findings indicate that the...

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PMID: 22575637
DOI: 10.1016/j.biocel.2012.04.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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