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GSK 3 inhibitor‐ BIO regulates proliferation of female germline stem cells from the postnatal mouse ovary

10 May 2012

Abstract excerpt

OBJECTIVE: It is widely believed that in most female mammalian neonates, all germ cells enter meiosis to form the primary oocyte at the end of foetal development, and as a result, the postnatal mammalian ovary harbours only a limited supply of oocytes that cannot be regenerated. However, this idea has been challenged by the discovery of the existence of female germline stem cells (FGSCs) in postnatal mammalian...

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PMID: 22571232
DOI: 10.1111/j.1365-2184.2012.00821.x

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