Article
Uncoupling protein-2 45-base pair insertion/deletion polymorphism: is there an association with severe obesity and weight loss in morbidly obese subjects?
Metabolic syndrome and related disorders - 1 Aug 2012
Papazoglou Dimitrios, Papathanasiou Pantelis, Papanas Nikolaos, Papatheodorou Konstantinos, Chatziangeli Eleni, Nikitidis Ioannis, Kotsiou Stamatia, Maltezos Efstratios
Abstract excerpt
BACKGROUND: Uncoupling proteins are attractive candidate genes for obesity and type 2 diabetes mellitus. Our aim was to investigate the potential association of the uncoupling protein-2 (UCP2) 45-bp insertion/deletion (ins/del) polymorphism with obesity, as well as the potential effect of this polymorphism on weight loss variability in severely obese subjects. METHODS: A total of 158 severely obese subjects (94...
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