Article
Proteomic analysis of the impact of static culturing on the expansion of rat bone marrow mesenchymal stem cells.
Biotechnology letters - 1 Aug 2012
Peter Stefan, Evans Caroline, Ow Saw Y, Scutt Andy M, Wright Phillip C, Biggs Catherine A
Abstract excerpt
The clinical potential of mesenchymal stem cells (MSC) in tissue engineering and regenerative medicine is due to their self-renewal, proliferation and multi-lineage differentiation potential. Clinical use requires large cell numbers; which can, theoretically, be generated by ex vivo expansion of plastic adherent, MSC subpopulation, of bone marrow cells (BMC). Effects of serial culture on MSC phenotype were...
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