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Article

Midkine promotes proliferation of primordial germ cells by inhibiting the expression of the deleted in azoospermia-like gene.

Endocrinology - 1 Jul 2012

Shen Wei, Park Bong-Wook, Toms Derek, Li Julang

Abstract excerpt

Primordial germ cell (PGC) development is an area of research that is hampered by low cell numbers as well as difficulty in isolation. They are, however, required for the production of gametes and as such represent an important area of understanding that has widespread implications for fertility and reproductive technologies. Here we investigated the role of the heparin-binding growth factor midkine (MK) on PGC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22564978
DOI: 10.1210/en.2011-1456

Genes

PGC
DAZL
DMC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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