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Article

Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis.

Disease models & mechanisms - 1 Jul 2012

Oehlers Stefan H, Flores Maria Vega, Hall Christopher J, Crosier Kathryn E, Crosier Philip S

Abstract excerpt

Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking r...

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Identifiers

PMID: 22563081
DOI: 10.1242/dmm.009365
PMCID: PMC3380709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22563081-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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