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Article

The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae.

Molecular microbiology - 1 Mar 2004

Morlot Cécile, Noirclerc-Savoye Marjolaine, Zapun André, Dideberg Otto, Vernet Thierry

Abstract excerpt

Bacterial division requires the co-ordination of membrane invagination, driven by the constriction of the FtsZ-ring, and concomitant cell wall synthesis, performed by the high-molecular-weight penicillin-binding proteins (HMW PBPs). Using immunofluorescence techniques, we show in Streptococcus pneumoniae that this co-ordination requires PBP3, a D,D-carboxypeptidase that degrades the substrate of the HMW PBPs. In...

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PMID: 15009891
DOI: 10.1046/j.1365-2958.2003.03953.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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