Article
Low IgG2 and polysaccharide response in a T cell receptor expression defect.
European journal of immunology - 1 Nov 1990
Regueiro J R, Perez-Aeiego P, Aparicio P, Martinez C, Morales P, Arnaiz-Villena A
Abstract excerpt
B lymphocytes require appropriate T lymphocyte cooperation to synthesize immunoglobulins (Ig). Such interaction presumably takes place after engagement of the T cell receptor (TcR) by antigen. The present work addresses B lymphocyte function (and phenotype) in a novel type of immunodeficiency which is characterized by a TcR expression defect. In contrast to expectations, the two affected siblings that were...
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