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Article

Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait.

Clinical immunology (Orlando, Fla.) - 1 Jun 2012

Al-Herz Waleed, Ragupathy Raj, Massaad Michel J, Al-Attiyah Raja'a, Nanda Arti, Engelhardt Karin R, Grimbacher Bodo, Notarangelo Luigi, Chatila Talal, Geha Raif S

Abstract excerpt

Deficiency of dedicator of cytokinesis 8 (DOCK8) is a newly described combined primary immunodeficiency disease. It was found to account for 15% of combined immune deficiency cases in the National Primary Immunodeficiency Disorders Registry in Kuwait, a country with high prevalence of consanguinity. We present the clinical, immunologic and molecular characteristics of 9 Kuwaiti patients with DOCK8 deficiency and...

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Identifiers

PMID: 22534316
DOI: 10.1016/j.clim.2012.03.002
PMCID: PMC3893030

Genes

DOCK8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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