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Article

Uncoupling protein 2 gene polymorphisms are associated with obesity.

Cardiovascular diabetology - 25 Apr 2012

Oktavianthi Sukma, Trimarsanto Hidayat, Febinia Clarissa A, Suastika Ketut, Saraswati Made R, Dwipayana Pande, Arindrarto Wibowo, Sudoyo Herawati, Malik Safarina G

Abstract excerpt

BACKGROUND: Uncoupling protein 2 (UCP2) gene polymorphisms have been reported as genetic risk factors for obesity and type 2 diabetes mellitus (T2DM). We examined the association of commonly observed UCP2 G(-866)A (rs659366) and Ala55Val (C > T) (rs660339) single nucleotide polymorphisms (SNPs) w...

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Identifiers

PMID: 22533685
DOI: 10.1186/1475-2840-11-41
PMCID: PMC3412711

Genes

UCP2
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22533685-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncoupling protein 2 gene polymorphisms are associated with obesity.PMID 22533685Read ↗

The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.Semantic proximity Read ↗

Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.Semantic proximity Read ↗

A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphisms are associated with childhood obesity and related metabolic disorders.Semantic proximity Read ↗

UCP2 A55V variant is associated with obesity and related phenotypes in an aboriginal community in Taiwan.Semantic proximity Read ↗

Unleash the Association of Mitochondrial Uncoupling Protein (UCP2) Promoter Variant (G-866A; rs659366) with Obesity: Stepping from a Case-Control Study to a Meta-analysis.Semantic proximity Read ↗

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans.Semantic proximity Read ↗

Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study.Semantic proximity Read ↗

The Gene-Lifestyle Interaction on Leptin Sensitivity and Lipid Metabolism in Adults: A Population Based Study.Semantic proximity Read ↗

Role of the Polymorphisms of Uncoupling Protein Genes in Childhood Obesity and Their Association with Obesity-Related Disturbances.Semantic proximity Read ↗

The common -866G/A polymorphism of the UCP2 gene in healthy Iranians compared with world populations.Semantic proximity Read ↗

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.Semantic proximity Read ↗

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