Article
Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.
PloS one - 1 Jan 2012
Gaj Pawel, Maryan Natalia, Hennig Ewa E, Ledwon Joanna K, Paziewska Agnieszka, Majewska Aneta, Karczmarski Jakub, Nesteruk Monika, Wolski Jan, Antoniewicz Artur A, Przytulski Krzysztof, Rutkowski Andrzej, Teumer Alexander, Homuth Georg, Starzyńska Teresa, Regula Jaroslaw, Ostrowski Jerzy
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) and colorectal cancer (CRC) are the most commonly diagnosed cancers and cancer-related causes of death in Poland. To date, numerous single nucleotide polymorphisms (SNPs) associated with susceptibility to both cancer types have been identified, but their effect on disease risk may differ among populations. METHODS: To identify new SNPs associated with PCa and CRC in the Polish...
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