Article
A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system.
Proceedings of the National Academy of Sciences of the United States of America - 8 May 2012
Lowe Elisabeth C, Baslé Arnaud, Czjzek Mirjam, Firbank Susan J, Bolam David N
Abstract excerpt
Signaling across the membrane in response to extracellular stimuli is essential for survival of all cells. In bacteria, responses to environmental changes are predominantly mediated by two-component systems, which are typically composed of a membrane-spanning sensor histidine kinase and a cytoplasmic response regulator. In the human gut symbiont Bacteroides thetaiotaomicron, hybrid two-component systems are a key...
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