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Whole-genome analyses of Korean native and Holstein cattle breeds by massively parallel sequencing.

PloS one - 1 Jan 2014

Choi Jung-Woo, Liao Xiaoping, Stothard Paul, Chung Won-Hyong, Jeon Heoyn-Jeong, Miller Stephen P, Choi So-Young, Lee Jeong-Koo, Yang Bokyoung, Lee Kyung-Tai, Han Kwang-Jin, Kim Hyeong-Cheol, Jeong Dongkee, Oh Jae-Don, Kim Namshin, Kim Tae-Hun, Lee Hak-Kyo, Lee Sung-Jin

Abstract excerpt

A main goal of cattle genomics is to identify DNA differences that account for variations in economically important traits. In this study, we performed whole-genome analyses of three important cattle breeds in Korea--Hanwoo, Jeju Heugu, and Korean Holstein--using the Illumina HiSeq 2000 sequencing platform. We achieved 25.5-, 29.6-, and 29.5-fold coverage of the Hanwoo, Jeju Heugu, and Korean Holstein genomes,...

Topics

Animals
Breeding
Cattle
DNA Copy Number Variations
Genome
Genomics
High-Throughput Nucleotide Sequencing
Homozygote
INDEL Mutation
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Republic of Korea

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Open in PubMed Open full text

Identifiers

PMID: 24992012
DOI: 10.1371/journal.pone.0101127
PMCID: PMC4081042

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