Article
OXPHOS supercomplexes as a hallmark of the mitochondrial phenotype of adipogenic differentiated human MSCs.
PloS one - 1 Jan 2012
Hofmann Andreas D, Beyer Mandy, Krause-Buchholz Udo, Wobus Manja, Bornhäuser Martin, Rödel Gerhard
Abstract excerpt
Mitochondria are essential organelles with multiple functions, especially in energy metabolism. Recently, an increasing number of data has highlighted the role of mitochondria for cellular differentiation processes. Metabolic differences between stem cells and mature derivatives require an adaptation of mitochondrial function during differentiation. In this study we investigated alterations of the mitochondrial...
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